LRRC26 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 0.5 - 1 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	LRRC26 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LRRC26. The immunogen is located within the last 50 amino acids of LRRC26.
Isotype	IgG
Formulation	LRRC26 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	LRRC26 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 37 kDa; Observed: 48 kDa
Gene Name	leucine rich repeat containing 26
Database Link	NP_001013675 Entrez Gene 389816 Human UniProt ID Q2I0M4
Background	The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues (1). LRRC26 was later found to negatively regulate the NF-kappaB activation and suppresses tumor growth and metastasis (2). LRRC26 can also act to selectively alter the efficacy of large conductance calcium-activated K (BK) channels (3).
Synonyms	bA350O14.10; CAPC
Reference Data
Protein Families	Transmembrane

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