TMEM107 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	TMEM107 antibody was raised against a 19 amino acid peptide near the amino terminus of human TMEM107.
Isotype	IgG
Formulation	TMEM107 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	TMEM107 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 16 kDa; Observed: 19 kDa
Gene Name	transmembrane protein 107
Database Link	NP_115730 Entrez Gene 84314 Human UniProt ID Q6UX40
Background	Transmembrane protein 107 (TMEM 107) is critical for cilia formation and embryonic patterning (1). It is a 139 amino acid transmembrane protein encoded by a gene that maps to human chromosome 17 which is associated with two key tumor suppressor genes p53 and BRCA1 (1,2). TMEM107 is required for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with Gli2 and Gli3 to pattern ventral and intermediate neuronal cell types (1,3). TMEM107 is also a strong candidate gene for central areolar choroidal dystrophy (CACD) (1-3).
Synonyms	GRVS638; PRO1268
Reference Data

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