CD272 (BTLA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	BTLA antibody was raised against a 17 amino acid peptide near the center of human BTLA.
Isotype	IgG
Formulation	BTLA Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	BTLA Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 32 kDa; Observed: 40 kDa
Gene Name	B and T lymphocyte associated
Database Link	NP_861445 Entrez Gene 151888 Human UniProt ID Q7Z6A9
Background	The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1). Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2). Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3).
Synonyms	BTLA1; CD272
Reference Data
Protein Families	Transmembrane

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