FCHO2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	FCHO2 antibody was raised against a 15 amino acid synthetic peptide near the center of human FCHO2.
Isotype	IgG
Formulation	FCHO2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	FCHO2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	FCH domain only 2
Database Link	NP_620137 Entrez Gene 218503 MouseEntrez Gene 309129 RatEntrez Gene 115548 Human UniProt ID Q0JRZ9
Background	FCHO2 Antibody: FCHO2 (FCH domain only 2) is a ubiquitously expressed member of the FCFBS superfamily characterized by FES-CIP4 homology (FCH) domain, an FBH domain, and an SH3 domain. Both FCHO2 and the related protein FCHO1 are mediators of clathrin-mediated endocytosis, acting to sculpt the initial bud site and recruit the clathrin machinery for clathrin-coated vesicle formation. FCHO2 binds to Eps15, an important adaptor protein in clathrin-mediated endocytosis.
Synonyms	FCH domain only 2
Reference Data

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