ZNF346 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	ZNF346 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human ZNF346.
Isotype	IgG
Formulation	ZNF346 (CT) Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	ZNF346 (CT) Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	zinc finger protein 346
Database Link	NP_036411 Entrez Gene 23567 Human UniProt ID Q9UL40
Background	ZNF346 (CT) Antibody: ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.
Synonyms	JAZ; Zfp346
Reference Data
Protein Families	Druggable Genome

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