KPNA7 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1 ug/mL, ICC: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KPNA7 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human KPNA7.
Isotype	IgG
Formulation	KPNA7 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	KPNA7 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	karyopherin subunit alpha 7
Database Link	NP_001139187 Entrez Gene 402569 Human UniProt ID A9QM74
Background	KPNA7 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.
Synonyms	IPOA8
Reference Data

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