Shank1 Mouse Monoclonal Antibody [Clone ID: S22-21]

Specifications

Product Data
Clone Name	S22-21
Applications	WB
Recommend Dilution	WB: 1-10ug/ml, IHC: 0.1-1.0ug/ml, IF: 1.0-10ug/ml
Reactivity	Mouse, Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Fusion protein amino acids 469-691 (SH3/PDZ domains) of rat Shank1
Isotype	IgG1
Formulation	PBS pH7.4, 50% glycerol
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	SH3 and multiple ankyrin repeat domains 1
Database Link	NP_113939 Entrez Gene 50944 HumanEntrez Gene 243961 MouseEntrez Gene 78957 Rat UniProt ID Q9WV48
Background	Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins . Shank1 specifically might be relevant to human autism spectrum disorders, due to its differential role in specific cognitive processes, along with its importance for synapse structure and function in vivo .
Synonyms	SPANK-1; SSTRIP; synamon
Note	Detects ~190-220 kDa (alternative splice variants). No cross-reactivity against Shank2 or Shank3.
Reference Data

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