Grin1 Mouse Monoclonal Antibody [Clone ID: S308-48]

Specifications

Product Data
Clone Name	S308-48
Applications	WB
Recommend Dilution	WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Fusion protein amino acids 42-361 (extracellular N-terminus) of rat NR1
Isotype	IgG1
Formulation	PBS pH7.4, 50% glycerol
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	glutamate ionotropic receptor NMDA type subunit 1
Database Link	NP_058706 Entrez Gene 2902 HumanEntrez Gene 14810 MouseEntrez Gene 24408 Rat UniProt ID P35439
Background	The NMDA receptor (NMDAR), a glutamate receptor, is the predominant molecular device for controllingsynaptic plasticity and memory function . The NMDA receptor forms a heterotetramer between two NR1 andtwo NR2 subunits (the subunits are also called glutamatebinding NMDA receptor subunits or GluN for short); twoobligatory NR1 subunits and two regionally localized NR2 subunits. A related gene family of NR3 A and B subunitshave an inhibitory effect on receptor activity. Multiple receptor isoforms with distinct brain distributions andfunctional properties arise by selective splicing of the NR1 transcripts and differential expression of the NR2subunits.
Synonyms	NMDA1; NMDAR1; NR1
Note	Detects ~105kDa.
Reference Data

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