TRP 7 (TRPC7) Mouse Monoclonal Antibody [Clone ID: S64A-36]

Specifications

Product Data
Clone Name	S64A-36
Applications	IF, WB
Recommend Dilution	WB: 1-10ug/ml, IHC: 0.1-1.0ug/ml, IF: 1.0-10ug/ml
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide amino acids 845-862 of human TRPC7
Isotype	IgG1
Formulation	PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	transient receptor potential cation channel subfamily C member 7
Database Link	NP_065122 Entrez Gene 26946 MouseEntrez Gene 282822 RatEntrez Gene 57113 Human UniProt ID Q9HCX4
Background	Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulartion by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway . TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure .
Synonyms	TRP7
Note	Detects ~100kDa.
Reference Data
Protein Families	Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane

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