BCR Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against A synthesized peptide derived from human Bcr around the phosphorylation site of Tyrosine 177
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	160 kDa
Gene Name	BCR, RhoGEF and GTPase activating protein
Database Link	NP_004318 Entrez Gene 110279 MouseEntrez Gene 613 Human UniProt ID P11274
Background	Bcr is a serine/threonine and GTPase-activating protein (GAP). breakpoint cluster region protein. GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them.
Synonyms	ALL; BCR1; CML; D22S11; D22S662; PHL
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Chronic myeloid leukemia, Pathways in cancer

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