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MCM7 Rabbit Polyclonal Antibody
CAT＃: TA324302S
Anti-MCM7 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Jurkat cells IHC: 15-50 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm, Nucleus |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a C terminal 300 amino acids of human minichromosome maintenance complex component 7 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 81 kDa |
| Gene Name | minichromosome maintenance complex component 7 |
| Database Link | |
| Background | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2; 4 and 6 proteins possesses DNA helicase activity; and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase; CDK4; is found to associate with this protein; and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Synonyms | CDC47; MCM2; P1.1-MCM3; P1CDC47; P85MCM; PNAS146; PPP1R104 |
| Reference Data | |
| Protein Families | Transcription Factors |
| Protein Pathways | Cell cycle, DNA replication |
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Rabbit anti-MCM7 Polyclonal Antibody
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