PRMT2 Rabbit Polyclonal Antibody
CAT#: TA324181S
Anti-PRMT2 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 6650.00
CNY 3080.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 25-100 Positive control: Human tonsil Predicted cell location: Cytoplasm, Nucleus |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 219-433 amino acids of human protein arginine methyltransferase 2 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | protein arginine methyltransferase 2 |
| Database Link | |
| Background | Protein arginine N-methyltransferase 2?is an?enzyme?that in humans is encoded by the?PRMT2?gene. Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3; FBL; histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR; PPARG; RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation. |
| Synonyms | HRMT1L1 |
| Reference Data | |
| Protein Families | Druggable Genome |
Documents
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