IL31RA Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human tonsil Predicted cell location: Cell membrane
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 21-319 amino acids of Human Interleukin-31 receptor subunit alpha
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	interleukin 31 receptor A
Database Link	NP_620586 Entrez Gene 133396 Human UniProt ID Q8NI17
Background	The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor; with homology to gp130; is expressed on monocytes; and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer; or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Synonyms	CRL; CRL3; GLM-R; GLMR; GPL; hGLM-R; IL-31RA; PLCA2; PRO21384
Reference Data
Protein Families	Druggable Genome, Transmembrane

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