PRMT7 Rabbit Polyclonal Antibody
CAT＃: TA324051S
Anti-PRMT7 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 1280.00
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Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Human liver cancer tissue |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 526-692 amino acids of human protein arginine methyltransferase 7 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 78 kDa |
| Gene Name | protein arginine methyltransferase 7 |
| Database Link | |
| Background | Protein arginine methyltransferase 7?is a?protein?that in humans is encoded by the?PRMT7?gene.?Arginine?methylation?is an apparently irreversible protein modification catalyzed by arginine methyltransferases; such as PMT7; using?S-adenosylmethionine?(AdoMet) as the methyl donor. Arginine methylation is implicated in?signal transduction; RNA transport; and?RNA splicing. May be involved in etoposide-induced cytotoxicity; a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT). |
| Synonyms | FLJ10640; KIAA1933 |
| Reference Data | |
| Protein Families | Druggable Genome |
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