Adenylosuccinate Lyase (ADSL) Rabbit Polyclonal Antibody

CAT#: TA323761

Anti-ADSL Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 1999.00

CNY 3280.00


货期*
2周

规格
    • 100 ul

Product images

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Specifications

Product Data
Applications IHC
Recommend Dilution IHC: 15-50
Positive control: Human breast cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein corresponding to C terminal 250 amino acids of human adenylosuccinate lyase
Isotype IgG
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name adenylosuccinate lyase
Background Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms AMPS; ASASE; ASL
Reference Data
Protein Families Druggable Genome
Protein Pathways Alanine, aspartate and glutamate metabolism, Metabolic pathways, Purine metabolism
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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