NMDAR1 (GRIN1) Rabbit Polyclonal Antibody
CAT#: TA323549S
Anti-GRIN1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
                                                
                                                
                                                
                                                    CNY 300.00 
                                                    
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CNY 4840.00
Specifications
| Product Data | |
| Applications | IHC | 
| Recommend Dilution | IHC: 50-200 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm  | 
        
| Reactivity | Human, Mouse, Rat | 
| Host | Rabbit | 
| Clonality | Polyclonal | 
| Immunogen | Synthetic peptide corresponding to a region derived from 35-49 amino acids of human glutamate receptor, ionotropic, N-methyl D-aspartate 1 | 
| Isotype | IgG | 
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol | 
| Purification | Antigen affinity purification | 
| Conjugation | Unconjugated | 
| Storage Condition | Store at -20°C as received. | 
| Gene Name | glutamate ionotropic receptor NMDA type subunit 1 | 
| Database Link | |
| Background | The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors; members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses; which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms; possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. | 
| Synonyms | GluN1; MRD8; NMD-R1; NMDA1; NMDAR1; NR1 | 
| Reference Data | |
| Protein Families | Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane | 
| Protein Pathways | Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Huntington's disease, Long-term potentiation, Neuroactive ligand-receptor interaction | 
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