FAT3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 3985-4000 amino acids of human FAT tumor suppressor homolog 3 (Drosophila)
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	FAT atypical cadherin 3
Database Link	NP_001008781 Entrez Gene 191571 RatEntrez Gene 270120 MouseEntrez Gene 120114 Human UniProt ID Q8TDW7
Background	FAT1; FAT2; FAT3 and FAT4 are human homologs of Drosophila Fat; which is involved in tumor suppression and planar cell polarity (PCP). The atypical cadherin Fat3 ensures that retinal amacrine cells (ACs) develop this unipolar morphology. Fat3 expression was restricted to the nervous system; for example in the brain; it is expressed in a variety of regions and axon fascicles. However; its strongest expression was observed in the olfactory bulb and retina.
Synonyms	CDHF15; CDHR10; hFat3
Reference Data

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