alpha Adducin (ADD1) Rabbit Polyclonal Antibody
CAT#: TA323225S
Anti-ADD1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 4840.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-200 Positive control: Human cervical cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | adducin 1 |
| Database Link | |
| Background | Adducins are a family of cytoskeleton proteins encoded by three genes (alpha; beta; gamma). Adducin is a heterodimeric protein that consists of related subunits; which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive; hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast; beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however; not all variants have been fully described. |
| Synonyms | ADDA |
| Reference Data | |
| Protein Families | Druggable Genome |
Documents
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