GDI1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1:500-2000, WB: 1:200-1000, IHC: 1:25-50
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 11-209 amino acids of Human Rab GDP dissociation inhibitor alpha
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	51 kDa
Gene Name	GDP dissociation inhibitor 1
Database Link	NP_001484 Entrez Gene 14567 MouseEntrez Gene 25183 RatEntrez Gene 2664 Human UniProt ID P31150
Background	GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
Synonyms	1A; GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4
Reference Data
Protein Families	Druggable Genome

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