HDAC2 Rabbit Polyclonal Antibody
CAT#: TA323157S
Anti-HDAC2 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
CNY 300.00
CNY 1430.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 15-50 Positive control: Human breast cancer Predicted cell location: Nucleus |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 474-488 amino acids of Human histone deacetylase 2 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | histone deacetylase 2 |
| Database Link | |
| Background | This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes; and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A; H2B; H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins; including YY1; a mammalian zinc-finger transcription factor. Thus; it plays an important role in transcriptional regulation; cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. |
| Synonyms | HD2; RPD3; YAF1 |
| Reference Data | |
| Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
| Protein Pathways | Cell cycle, Chronic myeloid leukemia, Huntington's disease, Notch signaling pathway, Pathways in cancer |
Documents
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