HSPB2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human heart tissue lysate IHC: 100-200 Positive control: Human colorectal cancer Predicted cell location: Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Full length fusion protein
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	heat shock protein family B (small) member 2
Database Link	NP_001532 Entrez Gene 69253 MouseEntrez Gene 161476 RatEntrez Gene 3316 Human UniProt ID Q16082
Background	Heat shock protein beta-2?is a?protein?that in humans is encoded by the?HSPB2?gene. Alpha-B-crystallin is a member of the alphacrystallin/small heat-shock protein (HSP) family and under various neuropathologic conditions accumulates in reactive astrocytes and degenerating neurons. In the 5-prime flanking region of the CRYAB gene on 11q22-q23; where a constitutive DNaseI hypersensitive site is locatedHSPB2 has been shown to interact with TRAF6; HSPB8; Myotonic dystrophy protein kinase and CRYAB.
Synonyms	Hs.78846; HSP27; LOH11CR1K; MKBP
Reference Data

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