KCNA5 Rabbit Polyclonal Antibody
CAT＃: TA323044S
Anti-KCNA5 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
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CNY 300.00
CNY 1430.00
CNY 4840.00
Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Mouse spleen tissue |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 517-613 amino acids of human potassium voltage-gated channel, shaker-related subfamily, member 5 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 44 kDa |
| Gene Name | potassium voltage-gated channel subfamily A member 5 |
| Database Link | |
| Background | Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release; heart rate; insulin secretion; neuronal excitability; epithelial electrolyte transport; smooth muscle contraction; and cell volume. Four sequence-related potassium channel genes - shaker; shaw; shab; and shal - have been identified in Drosophila; and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel; voltage-gated; shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class; the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless; and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7).? |
| Synonyms | ATFB7; HCK1; HK2; HPCN1; KV1.5; PCN1 |
| Reference Data | |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
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