FOXN1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human cervical cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 586-600 amino acids of Human forkhead box N1
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	forkhead box N1
Database Link	NP_003584 Entrez Gene 8456 Human UniProt ID O15353
Background	Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia; resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency; the skin disorder congenital alopecia; and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed.
Synonyms	FKHL20; RONU; WHN
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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