IL18R Beta (IL18RAP) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: RAW264.7 cells
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 378-599 amino acids of human interleukin 18 receptor accessory protein
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	68 kDa
Gene Name	interleukin 18 receptor accessory protein
Database Link	NP_003844 Entrez Gene 16174 MouseEntrez Gene 8807 Human UniProt ID O95256
Background	Interleukin 18 receptor accessory protein; also known as?IL18RAP?and?CDw218b?(cluster of differentiationw218b); is a human?gene. The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP); a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-?B and MAPK8 (JNK) in response to IL18.
Synonyms	ACPL; CD218b; CDw218b; IL-1R-7; IL-1R7; IL-1RAcPL; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL18RB
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction

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