CEBP Alpha (CEBPA) Rabbit Polyclonal Antibody
CAT#: TA322760S
Anti-CEBPA Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
CNY 300.00
CNY 1430.00
CNY 3080.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-100 Positive control: Human tonsil Predicted cell location: Nucleus |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 82-100 amino acids of Human CCAAT/enhancer binding protein (C/EBP), alpha |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | CCAAT/enhancer binding protein alpha |
| Database Link | |
| Background | The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin; a protein that plays an important role in body weight homeostasis. Also; the encoded protein can interact with CDK2 and CDK4; thereby inhibiting these kinases and causing growth arrest in cultured cells. |
| Synonyms | C; CEBP; EBP-alpha |
| Reference Data | |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
| Protein Pathways | Acute myeloid leukemia, Pathways in cancer |
Documents
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