Cathepsin H (CTSH) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Human liver cancer tissue IHC: 10-50 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 116-335 amino acids of human cathepsin H
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	37 kDa
Gene Name	cathepsin H
Database Link	NP_004381 Entrez Gene 13036 MouseEntrez Gene 25425 RatEntrez Gene 1512 Human UniProt ID P09668
Background	The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains; both produced from a single protein precursor. The encoded protein; which belongs to the peptidase C1 protein family; can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors.
Synonyms	ACC-4; ACC-5; ACC4; ACC5; CPSB
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Lysosome

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