Smoothened (SMO) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human brain Predicted cell location: Cytoplasm
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 772-787 amino acids of human smoothened, frizzled family receptor
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	smoothened, frizzled class receptor
Database Link	NP_005622 Entrez Gene 25273 RatEntrez Gene 6608 Human UniProt ID Q99835
Background	The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein; a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.
Synonyms	FZD11; Gx; SMOH
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane
Protein Pathways	Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer

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