GLUR3 (GRIA3) Rabbit Polyclonal Antibody
CAT＃: TA322430S
Anti-GRIA3 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 300.00
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CNY 4840.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 25-100 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 290-302 amino acids of Human glutamate receptor, ionotropic, AMPA 3 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | glutamate ionotropic receptor AMPA type subunit 3 |
| Database Link | |
| Background | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits; arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors; and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms; which may vary in their signal transduction properties. |
| Synonyms | GluA3; GLUR-C; GLUR-K3; GLUR3; GLURC; MRX94 |
| Reference Data | |
| Protein Families | Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane |
| Protein Pathways | Long-term depression, Neuroactive ligand-receptor interaction |
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