VGLL1 Rabbit Polyclonal Antibody
CAT＃: TA322329S
Anti-VGLL1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
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CNY 300.00
CNY 1430.00
Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 2000-10000 WB positive control: 293T cells |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 62-75 amino acids of human vestigial like 1 (Drosophila) |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 29 kDa |
| Gene Name | vestigial like family member 1 |
| Database Link | |
| Background | The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member; TEF1; and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid; and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes; suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter; and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay. |
| Synonyms | TDU; VGL1 |
| Reference Data | |
| Protein Families | Transcription Factors |
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