Cyclin M3 (CNNM3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Mouse liver tissue IHC: 25-100 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 300 amino acids of human cyclin M3
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	76 kDa
Gene Name	cyclin and CBS domain divalent metal cation transport mediator 3
Database Link	NP_060093 Entrez Gene 94218 MouseEntrez Gene 26505 Human UniProt ID Q8NE01
Background	The ACDP3 gene; designated?CNNM3?by the HUGO Nomenclature Committee; encodes a deduced 707-amino acid protein. Northern blot analysis revealed ubiquitous expression of?CNNM3. Immunofluorescence studies showed that all 4 CNMM proteins are predominantly localized in the nucleus. Acdp3 contains 4 transmembrane domains; 2 CBS domains; a DUF21 domain; and a cNMP-binding domain. It also has large alanine- and leucine-rich regions. Northern blot analysis detected variable Acdp3 expression in all mouse tissues examined; with highest expression in brain; kidney; liver; and heart.
Synonyms	ACDP3
Reference Data
Protein Families	Transcription Factors, Transmembrane

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