SPATA17 Rabbit Polyclonal Antibody
CAT#: TA322067S
Anti-SPATA17 rabbit polyclonal antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
货期*
2周
规格
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 200-1000 WB positive control: Human liver cancer tissue IHC: 10-50 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to C terminal 300 amino acids of human spermatogenesis associated 17 |
Isotype | IgG |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 43 kDa |
Gene Name | spermatogenesis associated 17 |
Database Link | |
Background | Spata17?gene, which called MSRG11, by digital differential display of ESTs found only in testis. The deduced 292-amino acid protein was considered to be a member of the family of calmodulin (CaM)-binding proteins because it contained 3 short CaM-binding motifs containing conserved ile and gln residues (IQ motif). Spata17 protein was most abundant in the cytoplasm of round spermatids and elongating spermatids within seminiferous tubules of the adult testis. Expression gradually decreased in the manipulated testis of animals that underwent experimental unilateral cryptorchidism. Transient transfection experiments with a Spata17 expression construct in cultured spermatogonia GC-1 cells indicated that Spata17 accelerated apoptosis in a dose-dependent manner. |
Synonyms | IQCH; MSRG-11; MSRG11 |
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