CCKBR Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: Human stomach cancer tissue
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 39-53 amino acids of Human cholecystokinin B receptor
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	49 kDa
Gene Name	cholecystokinin B receptor
Database Link	NP_795344 Entrez Gene 12426 MouseEntrez Gene 25706 RatEntrez Gene 887 Human UniProt ID P32239
Background	This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK); regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor; which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.
Synonyms	CCK-B; CCK2R; GASR
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Calcium signaling pathway, Neuroactive ligand-receptor interaction

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