Neurogenin 1 (NEUROG1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Hela, A375, HepG2, Mouse testis tissue, 293T cell lysates IHC: 50-200 Positive control: Human tonsil Predicted cell location: Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 26-39 amino acids of Human neurogenin 1
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	26 kDa
Gene Name	neurogenin 1
Database Link	NP_006152 Entrez Gene 18014 MouseEntrez Gene 4762 Human UniProt ID Q92886
Background	Neurogenin-1?is a?protein?that in humans is encoded by the?NEUROG1?gene. Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. NEUROG1 has been shown to interact with CREB-binding protein and decapentaplegic homolog 1.
Synonyms	AKA; bHLHa6; Math4C; NEUROD3; ngn1
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors

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