GNAZ Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Human cerebrum tissue lysate IHC: 25-50 Positive control: Human colorectal cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 4-18 amino acids of Human guanine nucleotide binding protein (G protein), alpha z polypeptide
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	41 kDa
Gene Name	G protein subunit alpha z
Database Link	NP_002064 Entrez Gene 14687 MouseEntrez Gene 25740 RatEntrez Gene 2781 Human UniProt ID P19086
Background	Guanine nucleotide-binding protein G(z) subunit alpha?is a?protein?that in humans is encoded by the?GNAZgene. The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systems. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. GNAZ has been shown to interact with EYA2; RGS20 and RGS19.
Synonyms	alpha z polypeptide; guanine nucleotide binding protein; guanine nucleotide binding protein (G protein); transducin alpha
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Long-term depression

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