KGF (FGF7) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 10-50 Positive control: Human esophagus cancer Predicted cell location: Cell membrane, Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 179-182 amino acids of Human Fibroblast growth factor 7
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	fibroblast growth factor 7
Database Link	NP_002000 Entrez Gene 14178 MouseEntrez Gene 29348 RatEntrez Gene 2252 Human UniProt ID P21781
Background	The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities; and are involved in a variety of biological processes; including embryonic development; cell growth; morphogenesis; tissue repair; tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor; whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium; reepithelialization of wounds; hair development and early lung organogenesis.
Synonyms	HBGF-7; KGF
Reference Data
Protein Families	Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways	MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

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