ADFP (PLIN2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human liver cancer and mouse brain tissue IHC: 25-100 Positive control: Human lung cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 423-437 amino acids of human perilipin 2
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	48 kDa
Gene Name	perilipin 2
Database Link	NP_001113 Entrez Gene 11520 MouseEntrez Gene 101055843 MouseEntrez Gene 123 Human UniProt ID Q99541
Background	The protein encoded by this gene belongs to the perilipin family; members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material; and maybe involved in development and maintenance of adipose tissue. However; it is not restricted to adipocytes as previously thought; but is found in a wide range of cultured cell lines; including fibroblasts; endothelial and epithelial cells; and tissues; such as lactating mammary gland; adrenal cortex; Sertoli and Leydig cells; and hepatocytes in alcoholic liver cirrhosis; suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.
Synonyms	ADFP; ADRP
Reference Data
Protein Families	Druggable Genome

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