EP4 (PTGER4) Rabbit Polyclonal Antibody
CAT＃: TA321244S
Anti-PTGER4 Rabbit Polyclonal Antibody
Size: 100 ul
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Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: LoVo cells |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 458-473 amino acids of Human prostaglandin E receptor 4 (subtype EP4) |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 53 kDa |
| Gene Name | prostaglandin E receptor 4 |
| Database Link | |
| Background | The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1); regulate the level and stability of cyclooxygenase-2 mRNA; and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system; osteoporosis; as well as initiation of skin immune responses. |
| Synonyms | EP4; EP4R |
| Reference Data | |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
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