Myelin Protein Zero (MPZ) Rabbit Polyclonal Antibody
CAT＃: TA321148S
Anti-MPZ Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
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CNY 300.00
CNY 1430.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 5-20 Positive control: Human cervical cancer Predicted cell location: Cell membrane, Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | myelin protein zero |
| Database Link | |
| Background | This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies. The myelin sheath is a multi-layered membrane; unique to the nervous system; that functions as an insulator to greatly increase the velocity of axonal impulse conduction. The P0 glycoprotein; absent in the central nervous system;[1] is a major component of the myelin sheath in peripheral nerves. It comprises a large extracellular N-terminal domain; a single transmembrane (TM) region; and a smaller positively charged intracellular domain. |
| Synonyms | CHM; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; DSS; HMSNIB; MPP; P0 |
| Reference Data | |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs) |
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