alpha 1 Antitrypsin (SERPINA1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human serum IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 290-303 amino acids of Human Alpha-1-antitrypsin
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	47 kDa
Gene Name	serpin family A member 1
Database Link	NP_000286 Entrez Gene 5265 Human UniProt ID P01009
Background	The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase; plasmin; thrombin; trypsin; chymotrypsin; and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.
Synonyms	A1A; A1AT; AAT; alpha1AT; PI; PI1; PRO2275
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways	Complement and coagulation cascades

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