SYVN1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1-3µg/ml
Reactivity	Human, Rat, Dog
Host	Goat
Clonality	Polyclonal
Immunogen	internal region of NP_115807.1; NP_757385.1 (HERQHLEARLQS)
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	synoviolin 1
Database Link	NP_757385 Entrez Gene 361712 RatEntrez Gene 483746 DogEntrez Gene 84447 Human UniProt ID Q86TM6
Background	This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq, May 2011]
Synonyms	DER3; HRD1
Note	This antibody is expected to recognize isoforms a and b (NP_115807.1; NP_757385.1).
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Ubiquitin mediated proteolysis

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.