IRF2BP2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	IRF2BP2 antibody was raised against an 17 amino acid synthetic peptide near the amino terminus of human IRF2BP2.
Isotype	IgG
Formulation	IRF2BP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	IRF2BP2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	interferon regulatory factor 2 binding protein 2
Database Link	NP_892017 Entrez Gene 359948 Human UniProt ID Q7Z5L9
Background	IRF2BP2 Antibody: IRF2BP2, like the related protein IRF2BP1, is a co-repressor that interacts specifically with the C-terminal repression domain of Interferon Regulatory Factor 2 (IRF2). IRF2BP2 is a direct target gene of p53 and is involved in cell survival during the p53 stress response, able to impede the p53-mediated transactivation of p21 and Bax. IRF2BP2 is also a co-factor of VGLL4 and is required to induce the expression of vascular endothelial growth factor A (VEGF-A) in muscle. It is normally found in the nucleus of skeletal muscle and cardiac cells, but can be found in the cytoplasm during skeletal muscle differentiation.
Synonyms	MGC72189
Reference Data
Protein Families	Druggable Genome

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