HIGD2A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	HIG2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human HIG2.
Isotype	IgG
Formulation	HIG2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	HIG2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	HIG1 hypoxia inducible domain family member 2A
Database Link	NP_001092256 Entrez Gene 192286 Human UniProt ID Q9BW72
Background	HIG2 Antibody: HIG1 and HIG2 (Hypoxia-inducible gene 1 and 2, respectively) are known to be induced by hypoxic conditions. HIG2 is induced by hypoxia and by glucose deprivation in cultured cells. In addition, tumor xenografts derived from human cervical cancer cells display increased expression of HIG1 and HIG2 when they are deprived of oxygen. Unlike HIG2, which is ubiquitously expressed and might be an activator and target of the canonical Wnt pathway, the function and the mechanisms underlying its regulation of HIG1 still remained unknown. The putative link between hypoxia and an oncogenic signaling pathway might play an important role in tumorigenesis.
Synonyms	RCF1b
Reference Data

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