SRARP Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	ERRF antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ERRF .
Isotype	IgG
Formulation	ERRF Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	ERRF Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 19 kDa; Observed: 15 kDa
Gene Name	chromosome 1 open reading frame 64
Database Link	NP_849162 Entrez Gene 277744 MouseEntrez Gene 149563 Human UniProt ID Q8NEQ6
Background	ERRF Antibody: The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.
Synonyms	ERRF
Reference Data

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