IL17RE Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Rabbit polyclonal IL-17RE antibody was raised against a 16 amino acid peptide near the center of human IL-17RE.
Isotype	IgG
Formulation	IL-17RE Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	IL-17RE Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	78 kDa
Gene Name	interleukin 17 receptor E
Database Link	NP_705616 Entrez Gene 132014 Human UniProt ID Q8NFR9
Background	IL-17RE Antibody: The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
Synonyms	FLJ23658; interleukin 17 receptor E; MGC71884; OTTHUMP00000158822
Reference Data

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