SYTL5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 5 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	SYTL5 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human SYTL5.
Isotype	IgG
Formulation	SYTL5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	SYTL5 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	synaptotagmin like 5
Database Link	NP_620135 Entrez Gene 236643 MouseEntrez Gene 302538 RatEntrez Gene 94122 Human UniProt ID Q8TDW5
Background	SYTL5 Antibody: SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.
Synonyms	slp5
Reference Data

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