ZNF336 (GZF1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 ug/mL, ICC: 2.5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	GZF1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human GZF1.
Isotype	IgG
Formulation	GZF1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	GZF1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	GDNF inducible zinc finger protein 1
Database Link	NP_071927 Entrez Gene 64412 Human UniProt ID Q9H116
Background	GZF1 Antibody: The GDNF-inducible zinc finger protein 1 (GZF1) is a sequence-specific transcriptional repressor with a BTB/POZ domain and ten zinc finger motifs whose expression is required for renal branching morphogenesis during kidney development. GZF1 binds to the 5'regulatory region of the homeodomain protein HOXA10, suggesting that GZF1 may play a role in morphogenesis other than kidney development. Recent experiments have indicated that GZF1 associates with nucleolin and this association is mediated by the first four zinc finger motifs of GZF1. It is thought that Nucleolin modulates the subcellular localization of GZF1 as well as its transcriptional repressor activity.
Synonyms	ZBTB23; ZNF336
Reference Data
Protein Families	Transcription Factors

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