WDR35 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	WDR35 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human WDR35.
Isotype	IgG
Formulation	WDR35 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	WDR35 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	WD repeat domain 35
Database Link	NP_001006658 Entrez Gene 57539 Human UniProt ID Q9P2L0
Background	WDR35 Antibody: WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities. WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia. Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.
Synonyms	CED2; IFT121; IFTA1; SRTD7
Reference Data

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