Rabex5 (RABGEF1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	RABEX5 antibody was raised against a 19 amino acid synthetic peptide near the center terminus of human RABEX5.
Isotype	IgG
Formulation	RABEX5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	RABEX5 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	RAB guanine nucleotide exchange factor 1
Database Link	NP_055319 Entrez Gene 56715 MouseEntrez Gene 360797 RatEntrez Gene 27342 Human UniProt ID Q9UJ41
Background	RABEX5 Antibody: RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic. RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.
Synonyms	rabex-5; RABEX5; RAP1
Reference Data

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