CRB1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Rabbit polyclonal CRB1 antibody was raised against an 18 amino acid peptide near the center of human CRB1.
Isotype	IgG
Formulation	CRB1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	CRB1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	142 kDa
Gene Name	crumbs 1, cell polarity complex component
Database Link	NP_001180569 Entrez Gene 23418 Human UniProt ID P82279
Background	CRB1 Antibody: CRB1 (Crumbs homolog 1) plays a role in photoreceptor morphogenesis in the retina. It may maintain cell polarization and adhesion. CRB1 is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. The first identified human homolog, CRB1, is expressed in retina and some parts of the brain, leaving room for another homolog to function in epithelial tissues. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis.
Synonyms	crumbs homolog 1; crumbs homolog 1 (Drosophila); LCA8; OTTHUMP00000033690; RP12
Reference Data

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