VPS39 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 0.5 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	VPS39 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human VPS39.
Isotype	IgG
Formulation	VPS39 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	VPS39 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	VPS39, HOPS complex subunit
Database Link	AAQ05978 Entrez Gene 23339 Human UniProt ID Q96JC1
Background	VPS39 Antibody: VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-beta response by coupling the TGF-beta receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6.5.
Synonyms	hVam6p; TLP; VAM6
Reference Data

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